中英對照讀新聞》Scientists publish the first complete human genome科學家發表第一個完整人類基因組
科學家首次公布完整人類基因組,有助於研究遺傳變異。示意圖。(路透檔案照)
◎陳成良
Scientists on Thursday published the first complete human genome, filling in gaps remaining after previous efforts while offering new promise in the search for clues regarding disease-causing mutations and genetic variation among the world’s 7.9 billion people.
科學家週四發表第一個完整人類基因組,填補了先前努力後仍存在的空白,同時為在全球79億人中尋找有關致病突變和遺傳變異的線索,帶來新希望。
Researchers in 2003 unveiled what was then billed as the complete sequence of the human genome. But about 8% of it had not been fully deciphered, mainly because it consisted of highly repetitive chunks of DNA that were difficult to mesh with the rest.
研究人員於2003年公布當時被稱為人類基因組的完整序列,但其中有大約8%沒有完全破譯,主要是因為這部分是由高度重覆的DNA片段組成,難以與其他部分相嚙合。
A consortium of scientists resolved that in research published in the journal Science. The work was initially made public last year before its formal peer review process.
一個科學家團隊解決了上述問題,並將成果發表在《科學》期刊。這項研究在經過正式同儕審查程序前,最初曾在去年公布。
The consortium’s full version is composed of 3.055 billion base pairs, the units from which chromosomes and our genes are built, and 19,969 genes that encode proteins.
這個團隊提供的完整版本,是由30億5500萬個鹼基對(構成染色體和基因的單位)和1萬9969個蛋白質編碼基因所組成。
新聞辭典
fill in:片語,填補、補充。例句:I’ll fill in the other details for you.(我將為你補充其他細節。)
repetitive:形容詞,重複的。例句:My job is boring and repetitive. (我的工作既無趣,重複性又高。)
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